Totally Spies! depicts three girlfriends 'with an attitude' who have to cope with their daily lives at high school as well as the unpredictable pressures of international espionage. They confront the most intimidating - and demented - of villains, each with their own special agenda for demonic, global rude behavior.
A villain with a Napoleonic complex uses his shrinking machine to bring the world down to size. B-story: Affected by the machine, Clover tries to return to normal size for her upcoming date.
The spies investigate alien abductions and a secret organization called GOOPER. In the b-story, Alex prepares for her driving test.
The cruise ship Juliet disappears in the Mediterranean Sea. Our heroines investigate and find out that the passengers, and even Clover, have been turned into human-animal hybrids by a famous fashion designer. In a B-story, Clover tries to impress a guy with some really tall shoes.
The girls investigate the disappearance of the California State Cheerleading Champions, The Honeybees. They have to deal with homicidal (sort of) cheerleading robots and come up with their own routine as the "WHOOP-ettes". In a B-story, Mandy rivals Sam into winning the Spelling Bee.
Sam falls for a seemingly nice boy at school, only to find out that he is using her to steal a top secret invisibility serum from the military. B-story: The girls decide they aren’t spending enough time together, so they plan a spa weekend in Palm Springs.
A villain invents a device which literally captures extreme sports stars and places them into an extreme video game. B-story: Alex falls for a teen idol who turns out to be a computer-generated personality.
